Short answer: yes — Escrow.com is a licensed, regulated provider and is safe for website and domain deals. Nearly every "escrow" loss actually comes from going off-platform or onto a fake escrow site.
A neutral third party holds the buyer's money until the asset is confirmed transferred, then releases it. The buyer can't grab the site without paying and the seller can't grab the money without delivering. That swap guarantee is the entire protection.
It's a licensed money transmitter that holds funds in trust and is the escrow built into major domain and website marketplaces. Used directly, it's the standard safe way to close — the same whether it's a domain or a whole site.
Escrow guarantees the swap, not the quality. It won't undo inflated traffic claims or fake revenue — that's what due diligence is for. Verify the asset before you approve release, because release is final.
The scam is a "buyer" who insists on an unfamiliar escrow site and sends you a link — that site is theirs. Only ever start the transaction yourself by typing escrow.com directly, and never move to wire, gift cards, or crypto "to save fees."